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About

Gennady Khvorykh

Hello! I’m Gennady Khvorykh, a bioinformatician from Institute of Molecular Genetics of National Research Centre «Kurchatov Institute» (Moscow, Russia).

Medical and population genetics are within the scope of my interests. I search for the genetic variants that contribute to ischemic stroke, using Genome-Wide Association Studies (GWAS) and machine learning (ML) approaches. Besides, I search for the genetic signals of natural selection, applying statistical methods to the genotypes of human populations.

A strong believer in modeling, the written word, and positive mood!

Publications

Full articles

  1. Ignatov, D., Khvorykh G., et all, Object-Attribute Biclustering for Elimination of Missing Genotypes in Ischemic Stroke Data, Communications in Computer and Information Science, 2020, (submitted).
  2. Khvorykh, G.V., Khrunin, A.V., Filippenkov, I.B., Stavchansky, V.V., Dergunova, L.V., Limborska, S.A., A workflow for selection of single nucleotide genomic markers for studying ischemic stroke genetics, Computational and Structural Biotechnology Journal, 2020, (submitted).
  3. Khvorykh, G.V., Mulyar, O.A., Fedorova, L., Khrunin, A.V., Limborska, S.A., Fedorov, A., Global picture of genetic relatedness and the evolution of humankind, Biology, 2020, (submitted).
  4. Khvorykh, G.V., Khrunin, A.V. imputeqc: an R package for assessing imputation quality of genotypes and optimizing imputation parameters. BMC Bioinformatics 21, 2020, 304. [pdf]
  5. Belova, V., Plakhina, D., Evfratov, S., Tsukanov, K., Khvorykh, G., Rakitko, A., Konoplyannikov, A., Ilinsky, V., Rebrikov, D., Korostin, D. NIPT Technique Based on the Use of Long Chimeric DNA Reads. Genes 2020, 11, 590. [pdf]
  6. Khrunin A.V., Khvorykh G.V., Fedorov A.N., Limborska S.A. Genomic landscape of the signals of positive natural selection in populations of Northern Eurasia: A view from Northern Russia. PLoS ONE, 2020, 15(2): e0228778. [pdf]
  7. Khrunin, A.V. and Khvorykh, G.V. Complex genetic history of Northeastern European and Western Siberian populations. Istoricheskaya Demographiya (Historical Demography), 2017, No 2 (20) (in Russian) [pdf].

Abstracts

  1. Khvorykh, G., Sharypov, R., Khrunin, A., Dyakonov, A., Limborska, S., Fedorov, A., The search for genetic risk factors of ischemic stroke with the genome-wide association study and machine learning methods, BMC Supplements, 2020 (in progress).
  2. Khvorykh, G., Vu, G., Khrunin, A., Genomic Signals of Adaptation in the Northern Ural and Western Siberian Populations, Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2020), The Twelfth International Multiconference, 06-10, July, 2020, Novosibirsk, Russia, p. 377, DOI 10.18699/BGRS/SB-2020-239. [pdf]
  3. Khrunin, A.V., Khvorykh, G.V., Limborska, S.A., The Regions of Extended Haplotype Homozygosity in the Chromosomes of Populations from European Part of Russia and Ural, Chromosome 2018: International Conference. August 20-20, 2018. Novosibirsk, Russia : Abstracts / Institute of Molecular and Cellular Biology SB RAS; Novosibirsk State University. - Novosibirsk, 2018. p. 192 (in Russian) [pdf]